Royal Air Force Typhoon FGR4s have conducted a mission with French warplanes in a combined operation targeting an underground arms cache in Syrian territory employed by the IS group, per a report from the UK Ministry of Defence.
The location, located using intelligence, was assessed as housing weapons and explosive materials, the release indicated, and was positioned in hills just to the north of the ancient city of Palmyra in central Syria.
"Our aircraft employed laser-guided Paveway IV weapons to strike a number of entry passages down to the depot... preliminary assessments indicate the strike was effective," the MoD said.
There was no sign of any harm to civilians in the attack conducted Saturday night and every plane involved returned to base without incident, the defence officials confirmed.
The Typhoon fighters were backed up by a Voyager tanker plane.
IS - also known as ISIS - imposed jihadist rule over significant areas in Iraq and Syria until 2019.
"This operation shows British leadership, and resolve to stand shoulder to shoulder with our partners, to eliminate any resurgence of IS and their violent and radical beliefs in the region," UK Defence Secretary the Defence Secretary remarked.
RAF aircraft have carried out overwatch operations over Syrian airspace to "forestall any attempted comeback" of the group subsequent to its routing at the Baghuz confrontation in 2019, the MoD reported.
"I extend gratitude to all the members of the UK armed forces participating in this strike for their expertise and their valour," Healey added. "They were among a great many UK service members deployed over Christmas and New Year. This mission, to remove terrorist threats who threaten our way of life, demonstrates how British military are always on standby, throughout the year, keeping Britain secure within its borders and strong abroad."
Last December, the US military executed what it called a "massive strike" on IS targets in the country, after an attack resulted in the deaths of two American soldiers and a civilian linguist in Palmyra.
The United Nations says Islamic State still has roughly 5-7 thousand fighters in Syria and Iraq.